2-Bromo-N-(p-toluenesulfonyl)pyrrole: A Robust Derivative of 2-Bromopyrrole

Abstract 2-Bromo-N-(P-toluenesulfonyl)pyrrole (2), a crystalline stable derivative of 2-bromopyrrole (1) has been prepared in 80% yield by bromination of pyrrole, followed by conversion to the N-(P-toluenesulfonyl) derivative. This compound is stable indefinitely at ambient temperature. Compound 2 i...

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Veröffentlicht in:Synlett 2003-10, Vol.2003 (13), p.1993-1996
Hauptverfasser: Knight, Lea W., Huffman, John W., Isherwood, Matthew L.
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container_end_page 1996
container_issue 13
container_start_page 1993
container_title Synlett
container_volume 2003
creator Knight, Lea W.
Huffman, John W.
Isherwood, Matthew L.
description Abstract 2-Bromo-N-(P-toluenesulfonyl)pyrrole (2), a crystalline stable derivative of 2-bromopyrrole (1) has been prepared in 80% yield by bromination of pyrrole, followed by conversion to the N-(P-toluenesulfonyl) derivative. This compound is stable indefinitely at ambient temperature. Compound 2 is an excellent substrate for Suzuki coupling with arylboronic acids.
doi_str_mv 10.1055/s-2003-42036
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title 2-Bromo-N-(p-toluenesulfonyl)pyrrole: A Robust Derivative of 2-Bromopyrrole
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