In Vitro Analysis of Esophageal Atresia Using a Whole-Embryo Culture System

Administration of Adriamycin to pregnant rats leads to the development of esophageal atresia with tracheo-esophageal fistula. This defect arises from failure of the trachea to develop normally from the primitive foregut; instead,the upper foregut differentiates into trachea, then continues to the lo...

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Veröffentlicht in:	European journal of pediatric surgery 2002-02, Vol.12 (1), p.3-7
Hauptverfasser:	Merei, J. M., Hasthorpe, S., Hutson, J. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced Animals Antibiotics, Antineoplastic - adverse effects Antineoplastic Agents - adverse effects Biological and medical sciences Culture Media Doxorubicin - adverse effects Embryo, Mammalian - drug effects Esophageal Atresia - chemically induced Esophageal Atresia - prevention & control Esophagus Female Gastroenterology. Liver. Pancreas. Abdomen Malformations Maternal Exposure Medical sciences Organ Culture Techniques - methods Original Article Pregnancy Rats Rats, Sprague-Dawley Time Factors Tracheoesophageal Fistula - chemically induced Tracheoesophageal Fistula - prevention & control
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