An Improved Synthesis of 2,3-Diamino-5,6-dichloropyrazine: A Useful Heterocyclic Scaffold

2,3-Diamino-5,6-dichloropyrazine represents a valuable but underexplored heterocyclic building block. Due to the use of harsh conditions and lack of selectivity surrounding the known literature synthesis, we developed a more accessible and selective three-step route from 2-aminopyrazine. Challenging...

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Veröffentlicht in:Synthesis (Stuttgart) 2024-12, Vol.56 (23), p.3587-3592
Hauptverfasser: Rigby, Jake M., Chantry, Andrew, Hemmings, Andrew M., Richards, Christopher J., Stephenson, G. Richard, Storr, Thomas E.
Format: Artikel
Sprache:eng
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