Simple Access to 3-(Hetero)arylated Derivatives of 2-Furoic Acid via Ru(II)-Catalyzed C3-H Arylation of 2-Furoylimidazole

A new approach for the preparation of a variety of 3-arylated 2-furoic acid derivatives has been developed. The approach involves selective Ru-catalyzed C3-H arylation of the furan moiety of readily available 2-furoyl-1-methylimidazole (using imidazole as a removable N-donor directing group), subseq...

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Veröffentlicht in:Synthesis (Stuttgart) 2024-10, Vol.56 (19), p.3063-3073
Hauptverfasser: Shepelenko, Konstantin E., Gnatiuk, Irina G., Lavrentev, Igor V., Minyaev, Mikhail E., Chernyshev, Victor M., Ananikov, Valentine P.
Format: Artikel
Sprache:eng
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