Polymorphonuclear Leukocyte Apoptosis Is Inhibited by Platelet-released Mediators, Role of TGFβ-1

Summary Platelets regulate several polymorphonuclear leukocyte (PMN) functions. We have found that thrombin-stimulated platelets potently inhibited PMN apoptosis. Cell-free supernatant from increasing concentrations of stimulated platelets inhibited PMN apoptosis in a dosedependent manner, with an e...

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Veröffentlicht in:Thrombosis and haemostasis 2000, Vol.83 (9), p.478-483
Hauptverfasser: Brunetti, Mauro, Martelli, Nicola, Manarini, Stefano, Mascetra, Nicola, Musiani, Piero, Cerletti, Chiara, Aiello, Francesca B., Evangelista, Virgilio
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Sprache:eng
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