Alkyl Nitrites: Novel Reagents for One-Pot Synthesis of 3,5-Disubstituted Isoxazoles from Aldoximes and Alkynes

Abstract An efficient, one-pot approach has been described for the synthesis of 3,5-disubstituted isoxazoles from substituted aldoximes (mixture of E and Z ) and alkynes, using alkyl nitrites under conventional heating conditions. The key nitrile oxide intermediates that are required for the synthes...

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Veröffentlicht in:	Synthesis (Stuttgart) 2016-11, Vol.48 (22), p.3996-4008
Hauptverfasser:	Kadam, Kishorkumar S., Gandhi, Thirumanavelan, Gupte, Amol, Gangopadhyay, A. K., Sharma, Rajiv
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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