Evaluation of Risk Factors for Recurrence of Laterosellar Meningiomas

Background : Evaluation of recurrence risk factors of meningiomas located in the laterosellar region is important to achieve and to adapt the therapeutic strategy. Therefore, we analyzed this risk of bone invasion or cavernous sinus involvement of these meningiomas. Methods : A retrospective study f...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Meyer, Mikael, Gay, E. G., Palombi, O. P.
Format: Tagungsbericht
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue S 02
container_start_page
container_title
container_volume 75
creator Meyer, Mikael
Gay, E. G.
Palombi, O. P.
description Background : Evaluation of recurrence risk factors of meningiomas located in the laterosellar region is important to achieve and to adapt the therapeutic strategy. Therefore, we analyzed this risk of bone invasion or cavernous sinus involvement of these meningiomas. Methods : A retrospective study from 1991 to 2007 included patients who were operated for a meningioma of the laterosellar region. They were classified in three groups according to their topography: (group 1) anterior clinoid meningiomas; (group 2) “en plaque” sphenoorbital or (group 3)cavernous sinus meningiomas. Their extension into the cavernous sinus or of the bone of the base skull was analyzed on MRI and at surgery. Results : A total of 94 patients were operated; out of which 29 patients relapsed (2 in group 1, 15 in group 2, and 12 in group 3). Sphenoorbital “en plaque” meningiomas had a HR = 4.40 risk for recurrence when the cavernous sinus is involved ( p = 0.007) with a 95% CI (1.49-12.98). Cavernous sinus meningiomas have a HR = 4.06 risk for recurrence when bone is invaded ( p = 0.073) with 95% CI (0.87-18.84). Cavernous sinus meningiomas have a likelihood of recurrence of 83% if the bone is invaded ( p = 0.05). Conclusion : For meningiomas of the laterosellar region, the bone invasion and the cavernous sinus involvement are the major risk factors for recurrence. The cavernous sinus involvement without a bone invasion is not a risk factor. Thus, in case of bone and cavernous involvement a combination of surgery and radiation therapy should be proposed.
doi_str_mv 10.1055/s-0034-1384194
format Conference Proceeding
fullrecord <record><control><sourceid>thieme_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1055_s_0034_1384194</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1055_s_0034_1384194</sourcerecordid><originalsourceid>FETCH-LOGICAL-c774-927bf35d5cd6d49b80dc3d2ce3a1c4e98b77cafa4e2c751516f54c4b2f038fa63</originalsourceid><addsrcrecordid>eNp1kFFLwzAUhYMoOOZefc4fyEyapGkfZXQqVISxB99Cmt5oZttI0gr-ezs2fNt9ORfuPYfDh9A9o2tGpXxIhFIuCOOFYKW4QouMlZzkXLxf_--c3aJVSgc6T86UEHSBqurHdJMZfRhwcHjn0xfeGjuGmLALEe_ATjHCYOF4rs0IMSToOhPxKwx--PChN-kO3TjTJViddYn222q_eSb129PL5rEmVilBykw1jstW2jZvRdkUtLW8zSxww6yAsmiUssYZAZlVkkmWOymsaDJHeeFMzpdofYq1c4kUwenv6HsTfzWj-ohBJ33EoM8YZgM5GcZPDz3oQ5jiMBe89P8HynReeQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype></control><display><type>conference_proceeding</type><title>Evaluation of Risk Factors for Recurrence of Laterosellar Meningiomas</title><source>PubMed Central</source><creator>Meyer, Mikael ; Gay, E. G. ; Palombi, O. P.</creator><creatorcontrib>Meyer, Mikael ; Gay, E. G. ; Palombi, O. P.</creatorcontrib><description>Background : Evaluation of recurrence risk factors of meningiomas located in the laterosellar region is important to achieve and to adapt the therapeutic strategy. Therefore, we analyzed this risk of bone invasion or cavernous sinus involvement of these meningiomas. Methods : A retrospective study from 1991 to 2007 included patients who were operated for a meningioma of the laterosellar region. They were classified in three groups according to their topography: (group 1) anterior clinoid meningiomas; (group 2) “en plaque” sphenoorbital or (group 3)cavernous sinus meningiomas. Their extension into the cavernous sinus or of the bone of the base skull was analyzed on MRI and at surgery. Results : A total of 94 patients were operated; out of which 29 patients relapsed (2 in group 1, 15 in group 2, and 12 in group 3). Sphenoorbital “en plaque” meningiomas had a HR = 4.40 risk for recurrence when the cavernous sinus is involved ( p = 0.007) with a 95% CI (1.49-12.98). Cavernous sinus meningiomas have a HR = 4.06 risk for recurrence when bone is invaded ( p = 0.073) with 95% CI (0.87-18.84). Cavernous sinus meningiomas have a likelihood of recurrence of 83% if the bone is invaded ( p = 0.05). Conclusion : For meningiomas of the laterosellar region, the bone invasion and the cavernous sinus involvement are the major risk factors for recurrence. The cavernous sinus involvement without a bone invasion is not a risk factor. Thus, in case of bone and cavernous involvement a combination of surgery and radiation therapy should be proposed.</description><identifier>ISSN: 2193-6331</identifier><identifier>EISSN: 2193-634X</identifier><identifier>DOI: 10.1055/s-0034-1384194</identifier><language>eng</language><ispartof>Journal of neurological surgery. Part B, Skull base, 2014, Vol.75 (S 02)</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,23930,23931,25140,27924,27925</link.rule.ids></links><search><creatorcontrib>Meyer, Mikael</creatorcontrib><creatorcontrib>Gay, E. G.</creatorcontrib><creatorcontrib>Palombi, O. P.</creatorcontrib><title>Evaluation of Risk Factors for Recurrence of Laterosellar Meningiomas</title><title>Journal of neurological surgery. Part B, Skull base</title><addtitle>J Neurol Surg B</addtitle><description>Background : Evaluation of recurrence risk factors of meningiomas located in the laterosellar region is important to achieve and to adapt the therapeutic strategy. Therefore, we analyzed this risk of bone invasion or cavernous sinus involvement of these meningiomas. Methods : A retrospective study from 1991 to 2007 included patients who were operated for a meningioma of the laterosellar region. They were classified in three groups according to their topography: (group 1) anterior clinoid meningiomas; (group 2) “en plaque” sphenoorbital or (group 3)cavernous sinus meningiomas. Their extension into the cavernous sinus or of the bone of the base skull was analyzed on MRI and at surgery. Results : A total of 94 patients were operated; out of which 29 patients relapsed (2 in group 1, 15 in group 2, and 12 in group 3). Sphenoorbital “en plaque” meningiomas had a HR = 4.40 risk for recurrence when the cavernous sinus is involved ( p = 0.007) with a 95% CI (1.49-12.98). Cavernous sinus meningiomas have a HR = 4.06 risk for recurrence when bone is invaded ( p = 0.073) with 95% CI (0.87-18.84). Cavernous sinus meningiomas have a likelihood of recurrence of 83% if the bone is invaded ( p = 0.05). Conclusion : For meningiomas of the laterosellar region, the bone invasion and the cavernous sinus involvement are the major risk factors for recurrence. The cavernous sinus involvement without a bone invasion is not a risk factor. Thus, in case of bone and cavernous involvement a combination of surgery and radiation therapy should be proposed.</description><issn>2193-6331</issn><issn>2193-634X</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2014</creationdate><recordtype>conference_proceeding</recordtype><sourceid>0U6</sourceid><recordid>eNp1kFFLwzAUhYMoOOZefc4fyEyapGkfZXQqVISxB99Cmt5oZttI0gr-ezs2fNt9ORfuPYfDh9A9o2tGpXxIhFIuCOOFYKW4QouMlZzkXLxf_--c3aJVSgc6T86UEHSBqurHdJMZfRhwcHjn0xfeGjuGmLALEe_ATjHCYOF4rs0IMSToOhPxKwx--PChN-kO3TjTJViddYn222q_eSb129PL5rEmVilBykw1jstW2jZvRdkUtLW8zSxww6yAsmiUssYZAZlVkkmWOymsaDJHeeFMzpdofYq1c4kUwenv6HsTfzWj-ohBJ33EoM8YZgM5GcZPDz3oQ5jiMBe89P8HynReeQ</recordid><startdate>20140617</startdate><enddate>20140617</enddate><creator>Meyer, Mikael</creator><creator>Gay, E. G.</creator><creator>Palombi, O. P.</creator><scope>0U6</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20140617</creationdate><title>Evaluation of Risk Factors for Recurrence of Laterosellar Meningiomas</title><author>Meyer, Mikael ; Gay, E. G. ; Palombi, O. P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c774-927bf35d5cd6d49b80dc3d2ce3a1c4e98b77cafa4e2c751516f54c4b2f038fa63</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2014</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Meyer, Mikael</creatorcontrib><creatorcontrib>Gay, E. G.</creatorcontrib><creatorcontrib>Palombi, O. P.</creatorcontrib><collection>Thieme Connect Journals Open Access</collection><collection>CrossRef</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Meyer, Mikael</au><au>Gay, E. G.</au><au>Palombi, O. P.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Evaluation of Risk Factors for Recurrence of Laterosellar Meningiomas</atitle><btitle>Journal of neurological surgery. Part B, Skull base</btitle><addtitle>J Neurol Surg B</addtitle><date>2014-06-17</date><risdate>2014</risdate><volume>75</volume><issue>S 02</issue><issn>2193-6331</issn><eissn>2193-634X</eissn><abstract>Background : Evaluation of recurrence risk factors of meningiomas located in the laterosellar region is important to achieve and to adapt the therapeutic strategy. Therefore, we analyzed this risk of bone invasion or cavernous sinus involvement of these meningiomas. Methods : A retrospective study from 1991 to 2007 included patients who were operated for a meningioma of the laterosellar region. They were classified in three groups according to their topography: (group 1) anterior clinoid meningiomas; (group 2) “en plaque” sphenoorbital or (group 3)cavernous sinus meningiomas. Their extension into the cavernous sinus or of the bone of the base skull was analyzed on MRI and at surgery. Results : A total of 94 patients were operated; out of which 29 patients relapsed (2 in group 1, 15 in group 2, and 12 in group 3). Sphenoorbital “en plaque” meningiomas had a HR = 4.40 risk for recurrence when the cavernous sinus is involved ( p = 0.007) with a 95% CI (1.49-12.98). Cavernous sinus meningiomas have a HR = 4.06 risk for recurrence when bone is invaded ( p = 0.073) with 95% CI (0.87-18.84). Cavernous sinus meningiomas have a likelihood of recurrence of 83% if the bone is invaded ( p = 0.05). Conclusion : For meningiomas of the laterosellar region, the bone invasion and the cavernous sinus involvement are the major risk factors for recurrence. The cavernous sinus involvement without a bone invasion is not a risk factor. Thus, in case of bone and cavernous involvement a combination of surgery and radiation therapy should be proposed.</abstract><doi>10.1055/s-0034-1384194</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2193-6331
ispartof Journal of neurological surgery. Part B, Skull base, 2014, Vol.75 (S 02)
issn 2193-6331
2193-634X
language eng
recordid cdi_crossref_primary_10_1055_s_0034_1384194
source PubMed Central
title Evaluation of Risk Factors for Recurrence of Laterosellar Meningiomas
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T15%3A40%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-thieme_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=Evaluation%20of%20Risk%20Factors%20for%20Recurrence%20of%20Laterosellar%20Meningiomas&rft.btitle=Journal%20of%20neurological%20surgery.%20Part%20B,%20Skull%20base&rft.au=Meyer,%20Mikael&rft.date=2014-06-17&rft.volume=75&rft.issue=S%2002&rft.issn=2193-6331&rft.eissn=2193-634X&rft_id=info:doi/10.1055/s-0034-1384194&rft_dat=%3Cthieme_cross%3E10_1055_s_0034_1384194%3C/thieme_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true