Catalyst-Free One-Pot Access to 3-Pyrazolylisoindolinone Derivatives

Abstract A series of 3-pyrazolylisoindolinone derivatives were synthesized by a concise, efficient, three-component reaction of a 2-formylbenzoic acid, a primary amine (or ammonium hydroxide), and a pyrazolone under catalyst-free conditions. This novel procedure has the advantages of easy handling,...

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Veröffentlicht in:Synthesis (Stuttgart) 2015-11, Vol.47 (21), p.3403-3411
Hauptverfasser: Che, Fengfeng, Fu, Zhijie, Shen, Tianhua, Lin, Yan, Song, Qingbao
Format: Artikel
Sprache:eng
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