Acoustic Neuroma Observation Leads to an Increase in Tinnitus Severity: Results of the 2007-2008 Acoustic Neuroma Association Survey
Objective: Tinnitus is a known presenting symptom of acoustic neuromas (ANs); however, observation has previously had an unpredictable impact on tinnitus. Most patients experience improvement with treatment, whereas others may worsen. Therefore, this study was designed to assess the overall impact o...
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creator | Van Gompel, Jamie J. Patel, Jaymin Danner, Chris Youssef, A. Sammy van Loveren, Harry R. Agazzi, Siviero |
description | Objective:
Tinnitus is a known presenting symptom of acoustic neuromas (ANs); however, observation has previously had an unpredictable impact on tinnitus. Most patients experience improvement with treatment, whereas others may worsen. Therefore, this study was designed to assess the overall impact of observation and treatment on tinnitus outcome in patients with acoustic tumors.
Methods:
The Acoustic Neuroma Association (ANA) 2007-2008 survey data were used. Tinnitus severity was graded both at presentation and at last follow-up for all patients questioned. The data were analyzed using Student
t
test and ANOVA analysis.
Results:
Overall, there were more patients receiving intervention (n = 1138) for their AN than observation (n = 289). Presenting tumor size positively correlated with tinnitus severity score (r2 = 0.01). Regardless of treatment (microsurgery or stereotactic radiation), tinnitus improved at last follow-up and worsened in those that were observed
(P
= 0.02). When comparing microsurgical options, retrosigmoid and translabyrinthine resections improved tinnitus symptoms (both
P
< 0.01). Stereotactic radiosurgery had a treatment effect similar to microsurgery.
Conclusion:
Presenting tinnitus severity correlates strongly with tumor size. Further, regardless of treatment, there appears to be an overall reduction in tinnitus severity for all forms of microsurgery and stereotactic radiosurgery. Importantly, observation leads to a worsening in patient-reported tinnitus severity and therefore should be weighed into the treatment recommendation. |
doi_str_mv | 10.1055/s-0033-1336159 |
format | Conference Proceeding |
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Tinnitus is a known presenting symptom of acoustic neuromas (ANs); however, observation has previously had an unpredictable impact on tinnitus. Most patients experience improvement with treatment, whereas others may worsen. Therefore, this study was designed to assess the overall impact of observation and treatment on tinnitus outcome in patients with acoustic tumors.
Methods:
The Acoustic Neuroma Association (ANA) 2007-2008 survey data were used. Tinnitus severity was graded both at presentation and at last follow-up for all patients questioned. The data were analyzed using Student
t
test and ANOVA analysis.
Results:
Overall, there were more patients receiving intervention (n = 1138) for their AN than observation (n = 289). Presenting tumor size positively correlated with tinnitus severity score (r2 = 0.01). Regardless of treatment (microsurgery or stereotactic radiation), tinnitus improved at last follow-up and worsened in those that were observed
(P
= 0.02). When comparing microsurgical options, retrosigmoid and translabyrinthine resections improved tinnitus symptoms (both
P
< 0.01). Stereotactic radiosurgery had a treatment effect similar to microsurgery.
Conclusion:
Presenting tinnitus severity correlates strongly with tumor size. Further, regardless of treatment, there appears to be an overall reduction in tinnitus severity for all forms of microsurgery and stereotactic radiosurgery. Importantly, observation leads to a worsening in patient-reported tinnitus severity and therefore should be weighed into the treatment recommendation.</description><identifier>ISSN: 2193-6331</identifier><identifier>EISSN: 2193-634X</identifier><identifier>DOI: 10.1055/s-0033-1336159</identifier><language>eng</language><ispartof>Journal of neurological surgery. Part B, Skull base, 2013, Vol.74 (S 01)</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,23930,23931,25140,27924,27925</link.rule.ids></links><search><creatorcontrib>Van Gompel, Jamie J.</creatorcontrib><creatorcontrib>Patel, Jaymin</creatorcontrib><creatorcontrib>Danner, Chris</creatorcontrib><creatorcontrib>Youssef, A. Sammy</creatorcontrib><creatorcontrib>van Loveren, Harry R.</creatorcontrib><creatorcontrib>Agazzi, Siviero</creatorcontrib><title>Acoustic Neuroma Observation Leads to an Increase in Tinnitus Severity: Results of the 2007-2008 Acoustic Neuroma Association Survey</title><title>Journal of neurological surgery. Part B, Skull base</title><addtitle>J Neurol Surg B</addtitle><description>Objective:
Tinnitus is a known presenting symptom of acoustic neuromas (ANs); however, observation has previously had an unpredictable impact on tinnitus. Most patients experience improvement with treatment, whereas others may worsen. Therefore, this study was designed to assess the overall impact of observation and treatment on tinnitus outcome in patients with acoustic tumors.
Methods:
The Acoustic Neuroma Association (ANA) 2007-2008 survey data were used. Tinnitus severity was graded both at presentation and at last follow-up for all patients questioned. The data were analyzed using Student
t
test and ANOVA analysis.
Results:
Overall, there were more patients receiving intervention (n = 1138) for their AN than observation (n = 289). Presenting tumor size positively correlated with tinnitus severity score (r2 = 0.01). Regardless of treatment (microsurgery or stereotactic radiation), tinnitus improved at last follow-up and worsened in those that were observed
(P
= 0.02). When comparing microsurgical options, retrosigmoid and translabyrinthine resections improved tinnitus symptoms (both
P
< 0.01). Stereotactic radiosurgery had a treatment effect similar to microsurgery.
Conclusion:
Presenting tinnitus severity correlates strongly with tumor size. Further, regardless of treatment, there appears to be an overall reduction in tinnitus severity for all forms of microsurgery and stereotactic radiosurgery. Importantly, observation leads to a worsening in patient-reported tinnitus severity and therefore should be weighed into the treatment recommendation.</description><issn>2193-6331</issn><issn>2193-634X</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2013</creationdate><recordtype>conference_proceeding</recordtype><sourceid>0U6</sourceid><recordid>eNp1kE1rAjEQhkNpoWK99pw_EJtsdjeb3kT6IUgF9dDbErMTjOimZLKC9_7wrii9lM5hZmDmnXd4CHkUfCx4UTwh41xKJqQsRaFvyCATWrJS5p-3v70U92SEuON9lELlOR-Q74kNHSZv6Qd0MRwMXWwQ4tEkH1o6B9MgTYGals5aG8EgUN_StW9bnzqkKzhC9On0TJeA3T4hDY6mLdCMc8X6VNE_BhPEYP3FYNXFI5weyJ0ze4TRtQ7J8vVlPX1n88XbbDqZM6uUZrLQjRbauXIjjWtyaATPKuMUNP1ImbyqjGlctbFaCpeVIFQjwGRKVFYYOSTjy1EbA2IEV39FfzDxVAtenxnWWJ8Z1leGvYBdBGnr4QD1LnSx7d_7b_8HsHdzcw</recordid><startdate>20130316</startdate><enddate>20130316</enddate><creator>Van Gompel, Jamie J.</creator><creator>Patel, Jaymin</creator><creator>Danner, Chris</creator><creator>Youssef, A. Sammy</creator><creator>van Loveren, Harry R.</creator><creator>Agazzi, Siviero</creator><scope>0U6</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20130316</creationdate><title>Acoustic Neuroma Observation Leads to an Increase in Tinnitus Severity: Results of the 2007-2008 Acoustic Neuroma Association Survey</title><author>Van Gompel, Jamie J. ; Patel, Jaymin ; Danner, Chris ; Youssef, A. Sammy ; van Loveren, Harry R. ; Agazzi, Siviero</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c779-359d919ff6b3afd4ed1028af7ed3597a488aadf8bc931f26e17d1ea2718c1a3</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2013</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Van Gompel, Jamie J.</creatorcontrib><creatorcontrib>Patel, Jaymin</creatorcontrib><creatorcontrib>Danner, Chris</creatorcontrib><creatorcontrib>Youssef, A. Sammy</creatorcontrib><creatorcontrib>van Loveren, Harry R.</creatorcontrib><creatorcontrib>Agazzi, Siviero</creatorcontrib><collection>Thieme Connect Journals Open Access</collection><collection>CrossRef</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Van Gompel, Jamie J.</au><au>Patel, Jaymin</au><au>Danner, Chris</au><au>Youssef, A. Sammy</au><au>van Loveren, Harry R.</au><au>Agazzi, Siviero</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Acoustic Neuroma Observation Leads to an Increase in Tinnitus Severity: Results of the 2007-2008 Acoustic Neuroma Association Survey</atitle><btitle>Journal of neurological surgery. Part B, Skull base</btitle><addtitle>J Neurol Surg B</addtitle><date>2013-03-16</date><risdate>2013</risdate><volume>74</volume><issue>S 01</issue><issn>2193-6331</issn><eissn>2193-634X</eissn><abstract>Objective:
Tinnitus is a known presenting symptom of acoustic neuromas (ANs); however, observation has previously had an unpredictable impact on tinnitus. Most patients experience improvement with treatment, whereas others may worsen. Therefore, this study was designed to assess the overall impact of observation and treatment on tinnitus outcome in patients with acoustic tumors.
Methods:
The Acoustic Neuroma Association (ANA) 2007-2008 survey data were used. Tinnitus severity was graded both at presentation and at last follow-up for all patients questioned. The data were analyzed using Student
t
test and ANOVA analysis.
Results:
Overall, there were more patients receiving intervention (n = 1138) for their AN than observation (n = 289). Presenting tumor size positively correlated with tinnitus severity score (r2 = 0.01). Regardless of treatment (microsurgery or stereotactic radiation), tinnitus improved at last follow-up and worsened in those that were observed
(P
= 0.02). When comparing microsurgical options, retrosigmoid and translabyrinthine resections improved tinnitus symptoms (both
P
< 0.01). Stereotactic radiosurgery had a treatment effect similar to microsurgery.
Conclusion:
Presenting tinnitus severity correlates strongly with tumor size. Further, regardless of treatment, there appears to be an overall reduction in tinnitus severity for all forms of microsurgery and stereotactic radiosurgery. Importantly, observation leads to a worsening in patient-reported tinnitus severity and therefore should be weighed into the treatment recommendation.</abstract><doi>10.1055/s-0033-1336159</doi><oa>free_for_read</oa></addata></record> |
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identifier | ISSN: 2193-6331 |
ispartof | Journal of neurological surgery. Part B, Skull base, 2013, Vol.74 (S 01) |
issn | 2193-6331 2193-634X |
language | eng |
recordid | cdi_crossref_primary_10_1055_s_0033_1336159 |
source | PubMed Central |
title | Acoustic Neuroma Observation Leads to an Increase in Tinnitus Severity: Results of the 2007-2008 Acoustic Neuroma Association Survey |
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