One-Pot, Two-Step Synthesis of Highly Functionalized 4-Indolyl/Pyrrolyl-Chromanes via a para-Quinone Methide Formation–1,8-Addition Sequence

An efficient one-pot, two-step synthesis of structurally diverse 4-indolyl-/pyrrolyl-chromanes was developed starting from o-propargylated salicylaldehydes, 2,6-dialkylphenols and indoles/pyrrole. This process begins with a sequential secondary amine-catalyzed formation of p-quinone methides followe...

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Veröffentlicht in:	Synthesis (Stuttgart) 2025-01, Vol.57 (1), p.218-228
Hauptverfasser:	Khatoon, Rafia, Jandial, Tanvi, Gupta, Anish, Kundan, Sujata, Sridharan, Vellaisamy
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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