Total Synthesis of Geranyl-Resorcinols Isolated from Mushrooms of Genus Hericium
Abstract This Short Review covers the total synthesis of tetraketide-based meroterpenoids, i.e. geranyl-resorcinols, isolated from the mushrooms of genus Hericium . Some of these compounds are believed to be involved in the unique health-promoting effects of Hericium erinaceus . Herein, more than se...
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| Veröffentlicht in: | Synthesis (Stuttgart) 2023-02, Vol.55 (3), p.417-432 |
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| container_title | Synthesis (Stuttgart) |
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| creator | Kobayashi, Shoji |
| description | Abstract
This Short Review covers the total synthesis of tetraketide-based meroterpenoids, i.e. geranyl-resorcinols, isolated from the mushrooms of genus
Hericium
. Some of these compounds are believed to be involved in the unique health-promoting effects of
Hericium erinaceus
. Herein, more than seventy natural products identified so far have been classified into seven-types based on both assumed biosynthetic pathways and chemical structures, and the successful total syntheses are summarized according to the structural type.
1 Introduction
2 Pioneering Synthetic Study
3 Total Synthesis of Geranyl-Resorcinol with a Geranyl Side Chain (Types 1, 3, and 6)
4 Total Synthesis of Geranyl-Resorcinol with an Oxidized Geranyl-Derived Side Chain (Types 2, 4, and 7)
5 Conclusion |
| doi_str_mv | 10.1055/a-1944-9623 |
| format | Article |
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This Short Review covers the total synthesis of tetraketide-based meroterpenoids, i.e. geranyl-resorcinols, isolated from the mushrooms of genus
Hericium
. Some of these compounds are believed to be involved in the unique health-promoting effects of
Hericium erinaceus
. Herein, more than seventy natural products identified so far have been classified into seven-types based on both assumed biosynthetic pathways and chemical structures, and the successful total syntheses are summarized according to the structural type.
1 Introduction
2 Pioneering Synthetic Study
3 Total Synthesis of Geranyl-Resorcinol with a Geranyl Side Chain (Types 1, 3, and 6)
4 Total Synthesis of Geranyl-Resorcinol with an Oxidized Geranyl-Derived Side Chain (Types 2, 4, and 7)
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This Short Review covers the total synthesis of tetraketide-based meroterpenoids, i.e. geranyl-resorcinols, isolated from the mushrooms of genus
Hericium
. Some of these compounds are believed to be involved in the unique health-promoting effects of
Hericium erinaceus
. Herein, more than seventy natural products identified so far have been classified into seven-types based on both assumed biosynthetic pathways and chemical structures, and the successful total syntheses are summarized according to the structural type.
1 Introduction
2 Pioneering Synthetic Study
3 Total Synthesis of Geranyl-Resorcinol with a Geranyl Side Chain (Types 1, 3, and 6)
4 Total Synthesis of Geranyl-Resorcinol with an Oxidized Geranyl-Derived Side Chain (Types 2, 4, and 7)
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This Short Review covers the total synthesis of tetraketide-based meroterpenoids, i.e. geranyl-resorcinols, isolated from the mushrooms of genus
Hericium
. Some of these compounds are believed to be involved in the unique health-promoting effects of
Hericium erinaceus
. Herein, more than seventy natural products identified so far have been classified into seven-types based on both assumed biosynthetic pathways and chemical structures, and the successful total syntheses are summarized according to the structural type.
1 Introduction
2 Pioneering Synthetic Study
3 Total Synthesis of Geranyl-Resorcinol with a Geranyl Side Chain (Types 1, 3, and 6)
4 Total Synthesis of Geranyl-Resorcinol with an Oxidized Geranyl-Derived Side Chain (Types 2, 4, and 7)
5 Conclusion</abstract><cop>Rüdigerstraße 14, 70469 Stuttgart, Germany</cop><pub>Georg Thieme Verlag KG</pub><doi>10.1055/a-1944-9623</doi><tpages>16</tpages><orcidid>https://orcid.org/0000-0002-8496-3685</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Synthesis (Stuttgart), 2023-02, Vol.55 (3), p.417-432 |
| issn | 0039-7881 1437-210X |
| language | eng |
| recordid | cdi_crossref_primary_10_1055_a_1944_9623 |
| source | Thieme Connect Journals |
| subjects | short review |
| title | Total Synthesis of Geranyl-Resorcinols Isolated from Mushrooms of Genus Hericium |
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