Facile Access to α-Substituted β-Thio Enals from 1,2,3-Triazines and Thiols

Facile Access to α-Substituted β-Thio Enals from 1,2,3-Triazines and Thiols

Abstract Herein, a chemoselective cascade addition reaction is reported, which starts from 1,2,3-triazines and thiols to access several different α-substituted β-thio enals and their derivatives in a green and efficient synthesis. In terms of applications, readily available substrates, diversity of...

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Veröffentlicht in:Synthesis (Stuttgart) 2022-10, Vol.54 (20), p.4472-4480
Hauptverfasser: Luo, Han, Lu, Qixing, Xu, Mingchuan, Gu, Mingxi, Li, Baosheng
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container_end_page 4480
container_issue 20
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container_title Synthesis (Stuttgart)
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creator Luo, Han
Lu, Qixing
Xu, Mingchuan
Gu, Mingxi
Li, Baosheng
description Abstract Herein, a chemoselective cascade addition reaction is reported, which starts from 1,2,3-triazines and thiols to access several different α-substituted β-thio enals and their derivatives in a green and efficient synthesis. In terms of applications, readily available substrates, diversity of products, and mild reaction system make this strategy highly attractive.
doi_str_mv 10.1055/a-1790-2282
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title Facile Access to α-Substituted β-Thio Enals from 1,2,3-Triazines and Thiols
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