Synthesis of Quinolino[1,2-c]quinazolin-6-one Derivatives via Formal (4+2)-Cycloaddition of Alkenes to Quinazolinе-Derived N-Acyliminium Cations: An Experimental and Theoretical Study

Abstract 3-Aryl-4-hydroxy-1-methyl-3,4-dihydroquinazolin-2(1 H )-ones were synthesized by reduction of 3-aryl-1-methylquinazoline-2,4(1 H ,3 H )-diones with sodium triethylborohydride and studied as precursors of N -acyliminium cations that were expected to be trapped with various alkenes as (4+2)-c...

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Veröffentlicht in:Synthesis (Stuttgart) 2022-05, Vol.54 (10), p.2395-2414
Hauptverfasser: Filatov, Alexander S., Larina, Anna G., Petrov, Mikhail L., Boitsov, Vitali M., Stepakov, Alexander V.
Format: Artikel
Sprache:eng
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