CuI-Catalyzed Ullmann-Type Coupling of Phenols and Thiophenols with 5-Substituted 1,2,3-Triiodobenzenes: Facile Synthesis of Mammary Carcinoma Inhibitor BTO-956 in One Step

Abstract A facile and unprecedented synthesis of 2,3-diiodinated or 2,6-diiodinated diaryl ether/thioether derivatives through regioselective Ullmann-type cross couplings of 5-substituted 1,2,3-triiodobenzenes and phenols/thiophenols is described. Remarkably, the coupling reactions are simply contro...

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Veröffentlicht in:Synthesis (Stuttgart) 2021-08, Vol.53 (15), p.2665-2675
Hauptverfasser: Al-Zoubi, Raed M., Altamimi, Reem M., Al-Jammal, Walid K., Shawakfeh, Khaled Q., Al-Zoubi, Mazhar S., Ferguson, Michael J., Zarour, Ahmad, Yassin, Aksam, Al-Ansari, Abdulla
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Sprache:eng
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