A role for Octamer binding protein motifs in the regulation of the proximal preprotachykinin-A promoter

We have recently developed cell line models that express the endogenous rat preprotachykinin-A (rPPT) gene and support reporter gene expression directed by the rPPT promoter. These are the neuronal derived cell line NF2C and the pancreatic cell lines RINm5F and a derivative RIN-1027-B2. Reporter gen...

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Veröffentlicht in:	Neuropeptides (Edinburgh) 2000-12, Vol.34 (6), p.348-354
Hauptverfasser:	Fiskerstrand, C.E., Newey, P., McGregor, G.P., Gerrard, L., Millan, F., Quinn, J.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Animals Binding Sites Biological and medical sciences Cell Line Chloramphenicol O-Acetyltransferase - biosynthesis Chloramphenicol O-Acetyltransferase - genetics DNA-Binding Proteins - metabolism Enhancer Elements, Genetic - genetics Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genes, Reporter HeLa Cells Host Cell Factor C1 Humans Luciferases - biosynthesis Luciferases - genetics Molecular and cellular biology Molecular genetics Mutagenesis, Site-Directed Neurons - cytology Octamer Transcription Factor-1 Pancreas - cytology Polymerase Chain Reaction Promoter Regions, Genetic - genetics Protein Precursors - genetics Rats Recombinant Fusion Proteins - biosynthesis Recombinant Fusion Proteins - genetics Regulatory Sequences, Nucleic Acid Repressor Proteins - chemistry Tachykinins - genetics Transcription Factors - metabolism Transcription, Genetic - drug effects Transcription, Genetic - genetics Transcription. Transcription factor. Splicing. Rna processing Transfection
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