Alcohol consumption in the absence of adequate nutrition may lead to activation of the glyoxylate cycle in man

The consumption of alcohol prior to food intake results in alcohol metabolism occurring in the liver, and the liver is often damaged in chronic alcoholics. This paper highlights the possibility that alcohol consumption in the absence of adequate nutrition after an extended period of time may lead to...

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Veröffentlicht in:Medical hypotheses 2002-05, Vol.58 (5), p.411-415
Hauptverfasser: Kokavec, A., Crowe, S.F.
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container_title Medical hypotheses
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creator Kokavec, A.
Crowe, S.F.
description The consumption of alcohol prior to food intake results in alcohol metabolism occurring in the liver, and the liver is often damaged in chronic alcoholics. This paper highlights the possibility that alcohol consumption in the absence of adequate nutrition after an extended period of time may lead to activation of the glyoxylate cycle, an energy pathway associated with the conversion of fat into carbohydrate which until recently was thought to only exist in plants and bacteria.
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subjects Alcohol Drinking - adverse effects
Alcohol Drinking - metabolism
Carbohydrate Metabolism
Eating
Energy Metabolism - drug effects
Ethanol - metabolism
Ethanol - toxicity
Glyoxylates - metabolism
Humans
Lipid Metabolism
Liver - drug effects
Liver - metabolism
Models, Biological
title Alcohol consumption in the absence of adequate nutrition may lead to activation of the glyoxylate cycle in man
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