Reversible valproate-induced choreiform movements
Valproate is an anticonvulsive drug whose mechanism of action is based on GABAergic systems. One of the infrequent adverse effects of valproate is choreiform movements. In our study, we report a patient having head trauma history with partial and secondary generalized seizures taking 1500 mg/day val...
Gespeichert in:
| Veröffentlicht in: | Seizure (London, England) England), 2002-04, Vol.11 (3), p.205-206 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 206 |
|---|---|
| container_issue | 3 |
| container_start_page | 205 |
| container_title | Seizure (London, England) |
| container_volume | 11 |
| creator | Gunal, Dilek Ince Guleryuz, Meliha Bingol, Canan Aykut |
| description | Valproate is an anticonvulsive drug whose mechanism of action is based on GABAergic systems. One of the infrequent adverse effects of valproate is choreiform movements. In our study, we report a patient having head trauma history with partial and secondary generalized seizures taking 1500 mg/day valproate. During the second month of the therapy, generalized chorea was observed. Since other aetiologic causes of chorea were excluded, acutely occurring chorea in the patient was thought to be related with valproate usage because of persistence of choreiform movements for days without any fluctuation. Valproate was stopped slowly and lamotrigine was added at a dose of 400 mg/day. Within a two-month period after cessation of the valproate, choreiform movements had disappeared. We thought that the history of head trauma and another antiepileptic drug usage were the risk factors for the occurrence of valproate-induced choreiform movements. |
| doi_str_mv | 10.1053/seiz.2001.0576 |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1053_seiz_2001_0576</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S105913110190576X</els_id><sourcerecordid>12018966</sourcerecordid><originalsourceid>FETCH-LOGICAL-c380t-90bbacae775171a476e1ee694d63170223cc80aec9416767b529d9b95f48bbea3</originalsourceid><addsrcrecordid>eNp1j1FLwzAUhYMobk5ffZT9gdZ7myZpHmXoFAaC6HNI0luMrOtIuoL-els28Mmnex--czgfY7cIOYLg94nCT14AYA5CyTM2R8GLrJBVdT7-IHSGHHHGrlL6AgBdIr9kMywAKy3lnOEbDRRTcFtaDna7j53tKQu7-uCpXvrPLlJoutgu226glnZ9umYXjd0mujndBft4enxfPWeb1_XL6mGTeV5Bn2lwznpLSglUaEslCYmkLmvJUUFRcO8rsOTHSVJJ5USha-20aMrKObJ8wfJjr49dSpEas4-htfHbIJjJ3UzuZnI3k_sYuDsG9gfXUv2Hn2RHoDoCNM4eAkWTfKDdKBoi-d7UXfiv-xciXGi0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Reversible valproate-induced choreiform movements</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Gunal, Dilek Ince ; Guleryuz, Meliha ; Bingol, Canan Aykut</creator><creatorcontrib>Gunal, Dilek Ince ; Guleryuz, Meliha ; Bingol, Canan Aykut</creatorcontrib><description>Valproate is an anticonvulsive drug whose mechanism of action is based on GABAergic systems. One of the infrequent adverse effects of valproate is choreiform movements. In our study, we report a patient having head trauma history with partial and secondary generalized seizures taking 1500 mg/day valproate. During the second month of the therapy, generalized chorea was observed. Since other aetiologic causes of chorea were excluded, acutely occurring chorea in the patient was thought to be related with valproate usage because of persistence of choreiform movements for days without any fluctuation. Valproate was stopped slowly and lamotrigine was added at a dose of 400 mg/day. Within a two-month period after cessation of the valproate, choreiform movements had disappeared. We thought that the history of head trauma and another antiepileptic drug usage were the risk factors for the occurrence of valproate-induced choreiform movements.</description><identifier>ISSN: 1059-1311</identifier><identifier>EISSN: 1532-2688</identifier><identifier>DOI: 10.1053/seiz.2001.0576</identifier><identifier>PMID: 12018966</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adult ; Anticonvulsants - adverse effects ; chorea ; Chorea - chemically induced ; Craniocerebral Trauma - complications ; Epilepsy - complications ; Epilepsy - drug therapy ; Epilepsy - physiopathology ; extrapyramidal ; Humans ; Male ; reversible ; Time Factors ; valproate ; Valproic Acid - adverse effects</subject><ispartof>Seizure (London, England), 2002-04, Vol.11 (3), p.205-206</ispartof><rights>2002 BEA Trading, Ltd</rights><rights>Copyright 2002 BEA Trading Ltd. Published by Elsevier Science Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c380t-90bbacae775171a476e1ee694d63170223cc80aec9416767b529d9b95f48bbea3</citedby><cites>FETCH-LOGICAL-c380t-90bbacae775171a476e1ee694d63170223cc80aec9416767b529d9b95f48bbea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1053/seiz.2001.0576$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12018966$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gunal, Dilek Ince</creatorcontrib><creatorcontrib>Guleryuz, Meliha</creatorcontrib><creatorcontrib>Bingol, Canan Aykut</creatorcontrib><title>Reversible valproate-induced choreiform movements</title><title>Seizure (London, England)</title><addtitle>Seizure</addtitle><description>Valproate is an anticonvulsive drug whose mechanism of action is based on GABAergic systems. One of the infrequent adverse effects of valproate is choreiform movements. In our study, we report a patient having head trauma history with partial and secondary generalized seizures taking 1500 mg/day valproate. During the second month of the therapy, generalized chorea was observed. Since other aetiologic causes of chorea were excluded, acutely occurring chorea in the patient was thought to be related with valproate usage because of persistence of choreiform movements for days without any fluctuation. Valproate was stopped slowly and lamotrigine was added at a dose of 400 mg/day. Within a two-month period after cessation of the valproate, choreiform movements had disappeared. We thought that the history of head trauma and another antiepileptic drug usage were the risk factors for the occurrence of valproate-induced choreiform movements.</description><subject>Adult</subject><subject>Anticonvulsants - adverse effects</subject><subject>chorea</subject><subject>Chorea - chemically induced</subject><subject>Craniocerebral Trauma - complications</subject><subject>Epilepsy - complications</subject><subject>Epilepsy - drug therapy</subject><subject>Epilepsy - physiopathology</subject><subject>extrapyramidal</subject><subject>Humans</subject><subject>Male</subject><subject>reversible</subject><subject>Time Factors</subject><subject>valproate</subject><subject>Valproic Acid - adverse effects</subject><issn>1059-1311</issn><issn>1532-2688</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1j1FLwzAUhYMobk5ffZT9gdZ7myZpHmXoFAaC6HNI0luMrOtIuoL-els28Mmnex--czgfY7cIOYLg94nCT14AYA5CyTM2R8GLrJBVdT7-IHSGHHHGrlL6AgBdIr9kMywAKy3lnOEbDRRTcFtaDna7j53tKQu7-uCpXvrPLlJoutgu226glnZ9umYXjd0mujndBft4enxfPWeb1_XL6mGTeV5Bn2lwznpLSglUaEslCYmkLmvJUUFRcO8rsOTHSVJJ5USha-20aMrKObJ8wfJjr49dSpEas4-htfHbIJjJ3UzuZnI3k_sYuDsG9gfXUv2Hn2RHoDoCNM4eAkWTfKDdKBoi-d7UXfiv-xciXGi0</recordid><startdate>20020401</startdate><enddate>20020401</enddate><creator>Gunal, Dilek Ince</creator><creator>Guleryuz, Meliha</creator><creator>Bingol, Canan Aykut</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20020401</creationdate><title>Reversible valproate-induced choreiform movements</title><author>Gunal, Dilek Ince ; Guleryuz, Meliha ; Bingol, Canan Aykut</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c380t-90bbacae775171a476e1ee694d63170223cc80aec9416767b529d9b95f48bbea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Anticonvulsants - adverse effects</topic><topic>chorea</topic><topic>Chorea - chemically induced</topic><topic>Craniocerebral Trauma - complications</topic><topic>Epilepsy - complications</topic><topic>Epilepsy - drug therapy</topic><topic>Epilepsy - physiopathology</topic><topic>extrapyramidal</topic><topic>Humans</topic><topic>Male</topic><topic>reversible</topic><topic>Time Factors</topic><topic>valproate</topic><topic>Valproic Acid - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gunal, Dilek Ince</creatorcontrib><creatorcontrib>Guleryuz, Meliha</creatorcontrib><creatorcontrib>Bingol, Canan Aykut</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Seizure (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gunal, Dilek Ince</au><au>Guleryuz, Meliha</au><au>Bingol, Canan Aykut</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reversible valproate-induced choreiform movements</atitle><jtitle>Seizure (London, England)</jtitle><addtitle>Seizure</addtitle><date>2002-04-01</date><risdate>2002</risdate><volume>11</volume><issue>3</issue><spage>205</spage><epage>206</epage><pages>205-206</pages><issn>1059-1311</issn><eissn>1532-2688</eissn><abstract>Valproate is an anticonvulsive drug whose mechanism of action is based on GABAergic systems. One of the infrequent adverse effects of valproate is choreiform movements. In our study, we report a patient having head trauma history with partial and secondary generalized seizures taking 1500 mg/day valproate. During the second month of the therapy, generalized chorea was observed. Since other aetiologic causes of chorea were excluded, acutely occurring chorea in the patient was thought to be related with valproate usage because of persistence of choreiform movements for days without any fluctuation. Valproate was stopped slowly and lamotrigine was added at a dose of 400 mg/day. Within a two-month period after cessation of the valproate, choreiform movements had disappeared. We thought that the history of head trauma and another antiepileptic drug usage were the risk factors for the occurrence of valproate-induced choreiform movements.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>12018966</pmid><doi>10.1053/seiz.2001.0576</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1059-1311 |
| ispartof | Seizure (London, England), 2002-04, Vol.11 (3), p.205-206 |
| issn | 1059-1311 1532-2688 |
| language | eng |
| recordid | cdi_crossref_primary_10_1053_seiz_2001_0576 |
| source | MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Anticonvulsants - adverse effects chorea Chorea - chemically induced Craniocerebral Trauma - complications Epilepsy - complications Epilepsy - drug therapy Epilepsy - physiopathology extrapyramidal Humans Male reversible Time Factors valproate Valproic Acid - adverse effects |
| title | Reversible valproate-induced choreiform movements |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-30T20%3A45%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Reversible%20valproate-induced%20choreiform%20movements&rft.jtitle=Seizure%20(London,%20England)&rft.au=Gunal,%20Dilek%20Ince&rft.date=2002-04-01&rft.volume=11&rft.issue=3&rft.spage=205&rft.epage=206&rft.pages=205-206&rft.issn=1059-1311&rft.eissn=1532-2688&rft_id=info:doi/10.1053/seiz.2001.0576&rft_dat=%3Cpubmed_cross%3E12018966%3C/pubmed_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/12018966&rft_els_id=S105913110190576X&rfr_iscdi=true |