Mallory body—A disease-associated type of sequestosome

Mallory bodies (MBs) consist of abnormal keratins, ubiquitin, heat shock proteins, and the protein p62. p62 is encoded by an immediate-early response gene that rapidly responds to a variety of extracellular signals involved in cell proliferation, differentiation, and particularly oxidative stress. I...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2002-05, Vol.35 (5), p.1053-1062
Hauptverfasser:	Stumptner, Cornelia, Fuchsbichler, Andrea, Heid, Hans, Zatloukal, Kurt, Denk, Helmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Animals Antibodies Biological and medical sciences Biopsy Blotting, Northern Blotting, Western Carrier Proteins - analysis Carrier Proteins - immunology Chemical and Drug Induced Liver Injury Dicarbethoxydihydrocollidine Humans Immediate-Early Proteins - analysis Immediate-Early Proteins - immunology Inclusion Bodies - chemistry Inclusion Bodies - pathology Inclusion Bodies - ultrastructure Investigative techniques, diagnostic techniques (general aspects) Keratins - analysis Keratins - immunology Liver - chemistry Liver - pathology Liver Diseases - pathology Male Medical sciences Mice Microscopy, Immunoelectron Miscellaneous. Technology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Proteins RNA, Messenger - analysis Sequestosome-1 Protein Transcription Factors Ubiquitin - analysis Ubiquitin - immunology
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