Differential expression of cyclooxygenase-2 (COX-2) in human bile duct epithelial cells and bile duct neoplasm

It is well known that chronic inflammatory conditions involving the bile ducts predispose to the development of bile duct carcinoma, although the relationship between chronic inflammation and malignant transformation is unclear. In this study, by combining immunohistochemistry and computer imaging t...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2001-10, Vol.34 (4), p.638-650
Hauptverfasser:	Hayashi, Nobuyasu, Yamamoto, Hirofumi, Hiraoka, Nobuaki, Dono, Keizo, Ito, Yasuhiro, Okami, Jiro, Kondo, Motoi, Nagano, Hiroaki, Umeshita, Koji, Sakon, Masato, Matsuura, Nariaki, Nakamori, Shoji, Monden, Morito
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile Duct Neoplasms - enzymology Bile Ducts - enzymology Biological and medical sciences Cell Division - drug effects Cholangitis, Sclerosing - enzymology Colonic Neoplasms - enzymology Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors - pharmacology Epithelial Cells - enzymology Gastroenterology. Liver. Pancreas. Abdomen Hepatocytes - enzymology Humans Immunohistochemistry Isoenzymes - analysis Isoenzymes - genetics Liver Cirrhosis, Biliary - enzymology Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Membrane Proteins Prostaglandin-Endoperoxide Synthases - analysis Prostaglandin-Endoperoxide Synthases - genetics Rabbits RNA, Messenger - analysis Tumor Cells, Cultured Tumors
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