Somatic isoform of angiotensin I–converting enzyme in the pathology of testicular germ cell tumors

Retained fetal expression of angiotensin I–converting enzyme (ACE, CD143) has recently been shown in intratubular germ cell neoplasms (IGCN) and invasive germ cell tumors (GCT), suggesting the somatic isoform (sACE) as a characteristic component of neoplastic germ cells. We analyzed the distribution...

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Veröffentlicht in:	Human pathology 2000-12, Vol.31 (12), p.1466-1476
Hauptverfasser:	Franke, Folker E., Pauls, Katharina, Kerkman, Luke, Steger, Klaus, Klonisch, Thomas, Metzger, Roman, Alhenc-Gelas, François, Burkhardt, Eberhard, Bergmann, Martin, Danilov, Sergei M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Alkaline Phosphatase Biological and medical sciences Carcinoma, Embryonal - enzymology Carcinoma, Embryonal - genetics Carcinoma, Embryonal - pathology Choriocarcinoma - enzymology Choriocarcinoma - genetics Choriocarcinoma - pathology DNA Primers - chemistry DNA, Neoplasm - analysis Endodermal Sinus Tumor - enzymology Endodermal Sinus Tumor - genetics Endodermal Sinus Tumor - pathology Germinoma - enzymology Germinoma - genetics Germinoma - pathology GPI-Linked Proteins Gynecology. Andrology. Obstetrics Humans Immunohistochemistry In Situ Hybridization Isoenzymes - genetics Isoenzymes - metabolism Male Male genital diseases Medical sciences Middle Aged Peptidyl-Dipeptidase A - genetics Peptidyl-Dipeptidase A - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Teratoma - enzymology Teratoma - genetics Teratoma - pathology Testicular Neoplasms - enzymology Testicular Neoplasms - genetics Testicular Neoplasms - pathology Testis - enzymology Testis - pathology Tumors
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