Randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis

Background & Aims: It has been suggested that losartan, an angiotensin II (A-II) type 1 receptor blocker, may have a pronounced portal pressure reducing effect, far greater than that of propranolol.This randomized controlled trial compared the hemodynamic and renal effects of continued 6-week ad...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2001-08, Vol.121 (2), p.382-388
Hauptverfasser:	González-Abraldes, Juan, Albillos, Agustin, Bañares, Rafael, Del Arbol, Luis Ruiz, Moitinho, Eduardo, Rodríguez, Claudio, González, Monica, Escorsell, Angels, García-Pagán, Juan Carlos, Bosch, Jaume
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antihypertensive Agents - administration & dosage Antihypertensive Agents - adverse effects Blood Pressure - drug effects Blood Urea Nitrogen Creatinine - blood Female Glomerular Filtration Rate - drug effects Humans Hypertension, Portal - drug therapy Liver Circulation - drug effects Liver Cirrhosis - complications Losartan - administration & dosage Losartan - adverse effects Male Middle Aged Propranolol - administration & dosage Propranolol - adverse effects Splanchnic Circulation - drug effects
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