Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: A double-blind, placebo-controlled trial

Background & Aims: An earlier pilot study from our liver unit suggested benefit from treatment with pentoxifylline (PTX), an inhibitor of tumor necrosis factor (TNF), in severe acute alcoholic hepatitis. The aim of the present study was to evaluate this treatment in a larger cohort of patients....

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2000-12, Vol.119 (6), p.1637-1648
Hauptverfasser:	Akriviadis, Evangelos, Botla, Ravi, Briggs, William, Han, Steven, Reynolds, Telfer, Shakil, Obaid
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Biological and medical sciences Cohort Studies Digestive system Disease Progression Double-Blind Method Female Hepatitis, Alcoholic - complications Hepatitis, Alcoholic - drug therapy Hepatitis, Alcoholic - mortality Hepatitis, Alcoholic - physiopathology Hepatorenal Syndrome - etiology Humans Male Medical sciences Middle Aged Morbidity Pentoxifylline - therapeutic use Pharmacology. Drug treatments Phosphodiesterase Inhibitors - therapeutic use Placebos Prospective Studies Survival Analysis Time Factors
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