Acute metabolic acidosis decreases muscle protein synthesis but not albumin synthesis in humans

Chronic metabolic acidosis induces negative nitrogen balance by either increased protein breakdown or decreased protein synthesis. Few data exist regarding effects of acute metabolic acidosis on protein synthesis. We investigated fractional synthesis rates (FSRs) of muscle protein and albumin, plasm...

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Veröffentlicht in:	American journal of kidney diseases 2001-12, Vol.38 (6), p.1199-1207
Hauptverfasser:	Kleger, Gian-Reto, Turgay, Meral, Imoberdorf, Reinhard, McNurlan, Margaret A., Garlick, Peter J., Ballmer, Peter E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis - chemically induced Acidosis - metabolism Adult Albumin Albumins - biosynthesis Ammonium Chloride Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Biopsy Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition Female Humans Intensive care medicine Male Medical sciences metabolic acidosis muscle Muscle Proteins - metabolism Muscle, Skeletal - metabolism Muscle, Skeletal - pathology nitrogen phenylalanine Potassium - urine protein synthesis Sodium - urine thyroid hormones
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