Role of the cystine-knot motif at the C-terminus of rat mucin protein Muc2 in dimer formation and secretion

DNA constructs based on the 534-amino-acid C-terminus of rat mucin protein Muc2 (RMC), were transfected into COS cells and the resultant 35S-labelled dimers and monomers were detected by SDS/PAGE of immunoprecipitates. The cystine-knot construct, encoding the C-terminal 115 amino acids, appeared in...

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Veröffentlicht in:	Biochemical journal 2001-07, Vol.357 (1), p.203-209
Hauptverfasser:	BELL, Sherilyn L., XU, Gongqiao, FORSTNER, Janet F.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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