Signal transduction pathway regulating prostaglandin EP3 receptor-induced neurite retraction: requirement for two different tyrosine kinases

We reported previously that activation of the prostaglandin E receptor EP3 subtype triggered neurite retraction through the small GTPase Rho-, and its target, RhoA-binding kinase α (ROKα)-, dependent pathway in EP3 receptor-expressing PC12 cells. Here we examined the involvement of tyrosine kinases...

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Veröffentlicht in:	Biochemical journal 1999-06, Vol.340 (2), p.365-369
Hauptverfasser:	AOKI, Junko, KATOH, Hironori, YASUI, Hidekazu, YAMAGUCHI, Yoshiaki, NAKAMURA, Kazuhiro, HASEGAWA, Hiroshi, ICHIKAWA, Atsushi, NEGISHI, Manabu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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