Desensitization of α2-adrenergic receptors in NG 108 15 cells by (–)-adrenaline and phorbol 12-myristate 13-acetate

alpha 2-Adrenergic receptors on NG 108 15 cell membranes were identified by [3H]rauwolscine binding: Bmax. = 661 +/- 81 fmol/mg of protein, Kd = 6.9 +/- 2.5 nM (mean +/- S.E.M., n = 6). On intact cells, stimulation of these receptors by (-)-adrenaline inhibited the prostaglandin-E1-stimulated adenyl...

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Veröffentlicht in:	Biochemical journal 1989-08, Vol.262 (1), p.245-251
Hauptverfasser:	Convents, A, De Backer, J P, André, C, Vauquelin, G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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