Metabonomic investigations of age- and batch-related variations in female NMRI mice using proton nuclear magnetic resonance spectroscopy

The NMRI outbred mouse model is widely used for studying metabolic disease, toxicity, and infection, yet information regarding baseline metabolism of this murine strain is relatively sparse. Using different batches of female NMRI mice, we assessed the stability of the metabolic phenotype with increa...

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Veröffentlicht in:	Molecular bioSystems 2013-12, Vol.9 (12), p.3155
Hauptverfasser:	Li, Jia V, Saric, Jasmina, Yap, Ivan K S, Utzinger, Jürg, Holmes, Elaine
Format:	Artikel
Sprache:	eng
Schlagworte:	Acclimatization Age Factors Animals Body Weight Feces - chemistry Female Metabolomics - methods Mice Plasma - chemistry Proton Magnetic Resonance Spectroscopy - methods Regression Analysis Urine - chemistry
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