SYNTHESIS OF A FULLY FUNCTIONALIZED CD RING-SYSTEM OF TAXOL

Key building blocks 16 and 17 related to taxol CD ring system have been synthesized in racemic form via a stereocontrolled and efficient sequence featuring a novel Diels-Alder reaction and oxetane formation.

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Veröffentlicht in:Journal of the Chemical Society. Chemical communications 1992 (16), p.1118-1120
Hauptverfasser: NICOLAOU, KC, LIU, JJ, HWANG, CK, DAI, WM, GUY, RK
Format: Artikel
Sprache:eng
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Zusammenfassung:Key building blocks 16 and 17 related to taxol CD ring system have been synthesized in racemic form via a stereocontrolled and efficient sequence featuring a novel Diels-Alder reaction and oxetane formation.
ISSN:0022-4936
DOI:10.1039/c39920001118