Size dependent macrophage responses and toxicological effects of Ag nanoparticles

The immune-response of macrophages is an important area of investigation since it represents the major pathway by which early-stage defense barriers are established in skin, lungs, and mucosal systems to counteract foreign objects. In this study, we have examined the size-dependent inflammatory and...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2011-04, Vol.47 (15), p.4382
Hauptverfasser:	Park, Jeongsin, Lim, Dae-Hyoun, Lim, Hyun-Jeong, Kwon, Taejung, Choi, Jin-sil, Jeong, Sohee, Choi, In-Hong, Cheon, Jinwoo
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Humans Inflammation - chemically induced Inflammation - metabolism Interleukin-8 - biosynthesis Macrophages - drug effects Macrophages - immunology Macrophages - metabolism Metal Nanoparticles - chemistry Metal Nanoparticles - toxicity Particle Size Phagocytosis - drug effects Phagocytosis - immunology Reactive Oxygen Species - metabolism Silver - chemistry Silver - toxicity
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Zusammenfassung:	The immune-response of macrophages is an important area of investigation since it represents the major pathway by which early-stage defense barriers are established in skin, lungs, and mucosal systems to counteract foreign objects. In this study, we have examined the size-dependent inflammatory and toxicological effects of nanostructured silver particles (nano-Ag) on macrophage immune cells.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c1cc10357a