Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer

Serum samples from kidney cancer patients and healthy controls were analyzed by both direct infusion mass spectrometry (DIMS) and liquid chromatography-mass spectrometry (LC-MS) with a high resolution ESI-Q-TOFMS. The classification and biomarker discovery capacities of the two methods were compared...

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Veröffentlicht in:	Analyst (London) 2010-01, Vol.135 (11), p.297-2978
Hauptverfasser:	Lin, Lin, Yu, Quan, Yan, Xiaomei, Hang, Wei, Zheng, Jiaxin, Xing, Jinchun, Huang, Benli
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analytical chemistry Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography, High Pressure Liquid Exact sciences and technology Female Humans Kidney Neoplasms - blood Kidney Neoplasms - metabolism Male Mass Spectrometry Metabolomics - methods Middle Aged Other chromatographic methods Sensitivity and Specificity Spectrometric and optical methods Spectrometry, Mass, Electrospray Ionization
Online-Zugang:	Volltext
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