A chloromethyl-triazole fluorescent chemosensor for O 6 -methylguanine DNA methyltransferase

Fluorescent chemosensors offer a direct means of measuring enzyme activity for cancer diagnosis, predicting drug resistance, and aiding in the discovery of new anticancer drugs. O -methylguanine DNA methyltransferase (MGMT) is a predictor of resistance towards anticancer alkylating agents such as te...

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Veröffentlicht in:Organic & biomolecular chemistry 2024-04, Vol.22 (14), p.2749-2753
Hauptverfasser: Ayan, Seylan, Rotaru, Adrian M, Kaye, Esther G, Juneau, Gabrielle, Das, Sunit, Wilds, Christopher J, Beharry, Andrew A
Format: Artikel
Sprache:eng
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