Conversion of amino-terephthalonitriles to multi-substituted single benzene fluorophores with utility in bioimaging

Substitution of two fluorine atoms of the tetrafluoroterephthalonitrile (TFTN) ring ( ortho to each other) by amine nucleophiles through S N Ar chemistry is achievable. However, tri- and tetra-substitution towards multi-substituted single benzene fluorophores (SBFs) is harder due to increased electr...

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Veröffentlicht in:	Organic & biomolecular chemistry 2024-01, Vol.22 (2), p.364-373
Hauptverfasser:	Raghava, Tanya, Chattopadhyay, Anjan, Banerjee, Subhadeep, Sarkar, Nivedita
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzene Charge transfer Chemical compounds Emission spectra Fluorescence Fluorine Fluorophores Lipophilic Medical imaging Nucleophiles Substitutes
Online-Zugang:	Volltext
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