The rapid construction and biological evaluation of densely substituted pyrrolo[1,2- a ]indoles via a BF 3 ·OEt 2 -assisted cascade approach

Lewis-acid cascade reactions promoted by BF ·OEt are reported for the synthesis of highly substituted pyrrolo[1,2- ]indoles and congeners of benzofuro[2,3- ]indoles. These reactions are highly regio- and diastereoselective towards generating up to five contiguous stereogenic centers, including two v...

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Veröffentlicht in:Organic & biomolecular chemistry 2023-12, Vol.21 (48), p.9659-9668
Hauptverfasser: Mali, Ghanshyam, Kumar Yadav, Vinay, Priya, Himani, Shukla, Manjari, Pandey, Peeyush, Kumar, Akhilesh, Paranjothy, Manikandan, Bhattacharyya, Sudipta, Erande, Rohan D
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Sprache:eng
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