The rapid construction and biological evaluation of densely substituted pyrrolo[1,2- a ]indoles via a BF 3 ·OEt 2 -assisted cascade approach
Lewis-acid cascade reactions promoted by BF ·OEt are reported for the synthesis of highly substituted pyrrolo[1,2- ]indoles and congeners of benzofuro[2,3- ]indoles. These reactions are highly regio- and diastereoselective towards generating up to five contiguous stereogenic centers, including two v...
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Veröffentlicht in: | Organic & biomolecular chemistry 2023-12, Vol.21 (48), p.9659-9668 |
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Hauptverfasser: | , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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