Flexible, self-healable, adhesive and wearable hydrogel patch for colorimetric sweat detection
Recent advances in wearable sweat sensors with noninvasive health monitoring capabilities have provided enormous potential for point-of-care testing (POCT) diagnostics and personalized medicine. In this paper, we present a flexible, self-healable, adhesive and wearable hydrogel patch for on-demand s...
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| Veröffentlicht in: | Journal of materials chemistry. C, Materials for optical and electronic devices Materials for optical and electronic devices, 2021-10, Vol.9 (41), p.14938-14945 |
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| container_issue | 41 |
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| container_title | Journal of materials chemistry. C, Materials for optical and electronic devices |
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| creator | Wang, Lirong Xu, Tailin He, Xuecheng Zhang, Xueji |
| description | Recent advances in wearable sweat sensors with noninvasive health monitoring capabilities have provided enormous potential for point-of-care testing (POCT) diagnostics and personalized medicine. In this paper, we present a flexible, self-healable, adhesive and wearable hydrogel patch for on-demand sweat colorimetric detection. Such a user-specific wearable hydrogel patch is simply prepared by the solvent displacement method, and can directly attach to human skin for
in situ
sweat sampling and colorimetric analysis without any complicated preparation steps. This wearable hydrogel patch shows excellent reliability and stability for measuring pH (4-9), glucose (0-2 mM), Cl
−
(0-100 mM) and Ca
2+
(0-16 mM) in human sweat through integration with smartphones. The analysis and detection of multiple sweat biomarkers of 15 healthy volunteers have been successfully realized by effectively converting the analyte concentration into RGB digital signals through the wearable hydrogel patch. Such a wearable hydrogel patch with flexible, self-healable, adhesive properties can achieve on-demand
in situ
sweat colorimetric detection, holding great potential in point-of-care devices.
A flexible, self-healable, adhesive and wearable hydrogel patch for sweat colorimetric analysis can achieve personalized
in situ
point-of-care detection. |
| doi_str_mv | 10.1039/d1tc03905a |
| format | Article |
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in situ
sweat sampling and colorimetric analysis without any complicated preparation steps. This wearable hydrogel patch shows excellent reliability and stability for measuring pH (4-9), glucose (0-2 mM), Cl
−
(0-100 mM) and Ca
2+
(0-16 mM) in human sweat through integration with smartphones. The analysis and detection of multiple sweat biomarkers of 15 healthy volunteers have been successfully realized by effectively converting the analyte concentration into RGB digital signals through the wearable hydrogel patch. Such a wearable hydrogel patch with flexible, self-healable, adhesive properties can achieve on-demand
in situ
sweat colorimetric detection, holding great potential in point-of-care devices.
A flexible, self-healable, adhesive and wearable hydrogel patch for sweat colorimetric analysis can achieve personalized
in situ
point-of-care detection.</description><identifier>ISSN: 2050-7526</identifier><identifier>EISSN: 2050-7534</identifier><identifier>DOI: 10.1039/d1tc03905a</identifier><language>eng</language><publisher>Cambridge: Royal Society of Chemistry</publisher><subject>Adhesive wear ; Adhesives ; Biomarkers ; Calcium ions ; Colorimetry ; Hydrogels ; Smartphones ; Sweat ; Wearable technology</subject><ispartof>Journal of materials chemistry. C, Materials for optical and electronic devices, 2021-10, Vol.9 (41), p.14938-14945</ispartof><rights>Copyright Royal Society of Chemistry 2021</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c322t-8b55756d5545944d83206aba8c8daf3ff1ff125b73e338493382d920cbb84733</citedby><cites>FETCH-LOGICAL-c322t-8b55756d5545944d83206aba8c8daf3ff1ff125b73e338493382d920cbb84733</cites><orcidid>0000-0003-4037-2856 ; 0000-0001-9503-2010 ; 0000-0002-0035-3821</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Wang, Lirong</creatorcontrib><creatorcontrib>Xu, Tailin</creatorcontrib><creatorcontrib>He, Xuecheng</creatorcontrib><creatorcontrib>Zhang, Xueji</creatorcontrib><title>Flexible, self-healable, adhesive and wearable hydrogel patch for colorimetric sweat detection</title><title>Journal of materials chemistry. C, Materials for optical and electronic devices</title><description>Recent advances in wearable sweat sensors with noninvasive health monitoring capabilities have provided enormous potential for point-of-care testing (POCT) diagnostics and personalized medicine. In this paper, we present a flexible, self-healable, adhesive and wearable hydrogel patch for on-demand sweat colorimetric detection. Such a user-specific wearable hydrogel patch is simply prepared by the solvent displacement method, and can directly attach to human skin for
in situ
sweat sampling and colorimetric analysis without any complicated preparation steps. This wearable hydrogel patch shows excellent reliability and stability for measuring pH (4-9), glucose (0-2 mM), Cl
−
(0-100 mM) and Ca
2+
(0-16 mM) in human sweat through integration with smartphones. The analysis and detection of multiple sweat biomarkers of 15 healthy volunteers have been successfully realized by effectively converting the analyte concentration into RGB digital signals through the wearable hydrogel patch. Such a wearable hydrogel patch with flexible, self-healable, adhesive properties can achieve on-demand
in situ
sweat colorimetric detection, holding great potential in point-of-care devices.
A flexible, self-healable, adhesive and wearable hydrogel patch for sweat colorimetric analysis can achieve personalized
in situ
point-of-care detection.</description><subject>Adhesive wear</subject><subject>Adhesives</subject><subject>Biomarkers</subject><subject>Calcium ions</subject><subject>Colorimetry</subject><subject>Hydrogels</subject><subject>Smartphones</subject><subject>Sweat</subject><subject>Wearable technology</subject><issn>2050-7526</issn><issn>2050-7534</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpFkE1LAzEQhoMoWGov3oWAN3E1H5vd7LGsVoWCl55dssnE3bI2NUnV_nvTVuoQ5s0MDzPJi9AlJXeU8Ore0KiTEqFO0IgRQbJS8Pz0eGfFOZqEsCQpJC1kUY3Q22yAn74d4BYHGGzWgRrUvlSmg9B_AVYrg79B-V0bd1vj3TsMeK2i7rB1Hms3ON9_QPS9xiGRERuIoGPvVhfozKohwORPx2gxe1zUz9n89emlns4zzRmLmWyFKEVhhMhFledGckYK1SqppVGWW0vTYaItOXAu8yolZipGdNvKvOR8jK4PY9fefW4gxGbpNn6VNjZMyJKIKn04UTcHSnsXggfbrNO7ld82lDQ7B5sHuqj3Dk4TfHWAfdBH7t9h_guvZmy4</recordid><startdate>20211028</startdate><enddate>20211028</enddate><creator>Wang, Lirong</creator><creator>Xu, Tailin</creator><creator>He, Xuecheng</creator><creator>Zhang, Xueji</creator><general>Royal Society of Chemistry</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0003-4037-2856</orcidid><orcidid>https://orcid.org/0000-0001-9503-2010</orcidid><orcidid>https://orcid.org/0000-0002-0035-3821</orcidid></search><sort><creationdate>20211028</creationdate><title>Flexible, self-healable, adhesive and wearable hydrogel patch for colorimetric sweat detection</title><author>Wang, Lirong ; Xu, Tailin ; He, Xuecheng ; Zhang, Xueji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c322t-8b55756d5545944d83206aba8c8daf3ff1ff125b73e338493382d920cbb84733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adhesive wear</topic><topic>Adhesives</topic><topic>Biomarkers</topic><topic>Calcium ions</topic><topic>Colorimetry</topic><topic>Hydrogels</topic><topic>Smartphones</topic><topic>Sweat</topic><topic>Wearable technology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Lirong</creatorcontrib><creatorcontrib>Xu, Tailin</creatorcontrib><creatorcontrib>He, Xuecheng</creatorcontrib><creatorcontrib>Zhang, Xueji</creatorcontrib><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Journal of materials chemistry. C, Materials for optical and electronic devices</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Lirong</au><au>Xu, Tailin</au><au>He, Xuecheng</au><au>Zhang, Xueji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Flexible, self-healable, adhesive and wearable hydrogel patch for colorimetric sweat detection</atitle><jtitle>Journal of materials chemistry. C, Materials for optical and electronic devices</jtitle><date>2021-10-28</date><risdate>2021</risdate><volume>9</volume><issue>41</issue><spage>14938</spage><epage>14945</epage><pages>14938-14945</pages><issn>2050-7526</issn><eissn>2050-7534</eissn><abstract>Recent advances in wearable sweat sensors with noninvasive health monitoring capabilities have provided enormous potential for point-of-care testing (POCT) diagnostics and personalized medicine. In this paper, we present a flexible, self-healable, adhesive and wearable hydrogel patch for on-demand sweat colorimetric detection. Such a user-specific wearable hydrogel patch is simply prepared by the solvent displacement method, and can directly attach to human skin for
in situ
sweat sampling and colorimetric analysis without any complicated preparation steps. This wearable hydrogel patch shows excellent reliability and stability for measuring pH (4-9), glucose (0-2 mM), Cl
−
(0-100 mM) and Ca
2+
(0-16 mM) in human sweat through integration with smartphones. The analysis and detection of multiple sweat biomarkers of 15 healthy volunteers have been successfully realized by effectively converting the analyte concentration into RGB digital signals through the wearable hydrogel patch. Such a wearable hydrogel patch with flexible, self-healable, adhesive properties can achieve on-demand
in situ
sweat colorimetric detection, holding great potential in point-of-care devices.
A flexible, self-healable, adhesive and wearable hydrogel patch for sweat colorimetric analysis can achieve personalized
in situ
point-of-care detection.</abstract><cop>Cambridge</cop><pub>Royal Society of Chemistry</pub><doi>10.1039/d1tc03905a</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-4037-2856</orcidid><orcidid>https://orcid.org/0000-0001-9503-2010</orcidid><orcidid>https://orcid.org/0000-0002-0035-3821</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2050-7526 |
| ispartof | Journal of materials chemistry. C, Materials for optical and electronic devices, 2021-10, Vol.9 (41), p.14938-14945 |
| issn | 2050-7526 2050-7534 |
| language | eng |
| recordid | cdi_crossref_primary_10_1039_D1TC03905A |
| source | Royal Society Of Chemistry Journals 2008- |
| subjects | Adhesive wear Adhesives Biomarkers Calcium ions Colorimetry Hydrogels Smartphones Sweat Wearable technology |
| title | Flexible, self-healable, adhesive and wearable hydrogel patch for colorimetric sweat detection |
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