Surface peptide functionalization of zeolitic imidazolate framework-8 for autonomous homing and enhanced delivery of chemotherapeutic agent to lung tumor cells

Chemotherapeutic agents used in treating certain cancer types operate in a non-selective manner tending to accumulate in normal, healthy tissue when high doses are used. To mitigate the toxicity effect resulting from this, there is an urgent need to develop active nano delivery systems capable of re...

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Veröffentlicht in:	Dalton transactions : an international journal of inorganic chemistry 2021-02, Vol.5 (7), p.2375-2386
Hauptverfasser:	Kamal, Nurul Akmarina Mohd Abdul, Abdulmalek, Emilia, Fakurazi, Sharida, Cordova, Kyle E, Abdul Rahman, Mohd Basyaruddin
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Gravimetric analysis Homing Lung cancer Metal-organic frameworks Nanoparticles Peptides Selectivity Size exclusion chromatography Toxicity Zeolites Zeta potential
Online-Zugang:	Volltext
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