The relative stability of trpzip1 and its mutants determined by computation and experiment

Six mutants of the tryptophan zipper peptide trpzip1 have been computationally and experimentally characterized. We determine the varying roles in secondary structure stability of specific residues through a mutation assay. Four of the mutations directly effect the Trp-Trp interactions and two of th...

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Veröffentlicht in:	RSC advances 2020-02, Vol.1 (11), p.652-6535
Hauptverfasser:	Bureau, Hailey R, Quirk, Stephen, Hernandez, Rigoberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Hydrogen bonding Molecular dynamics Mutation Peptides Structural stability Tryptophan
Online-Zugang:	Volltext
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