Total synthesis of tubulysin U and N 14 -desacetoxytubulysin H

A concise and efficient procedure for the total synthesis of tubulysin U and N14-desacetoxytubulysin H has been developed with high stereoselectivity on a gram scale. This synthesis features an elegant cascade one-pot process to install the challenging thiazole moiety and the employment of stereosel...

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Veröffentlicht in:	Organic & biomolecular chemistry 2020-07, Vol.18 (28), p.5349-5353
Hauptverfasser:	Long, Bohua, Tao, Cheng, Li, Yinghong, Zeng, Xiaobin, Cao, Meiqun, Wu, Zhengzhi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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