Time-resolved SANS reveals pore-forming peptides cause rapid lipid reorganization

Cells depend on proper lipid transport and their precise distribution for vital cellular function. Disruption of such lipid organization can be initiated by external agents to cause cell death. Here, we investigate two antimicrobial pore-forming peptides, alamethicin and melittin, and their influenc...

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Veröffentlicht in:	New journal of chemistry 2021-01, Vol.45 (1), p.447-456
Hauptverfasser:	Nguyen, Michael H. L, DiPasquale, Mitchell, Rickeard, Brett W, Yip, Caesar G, Greco, Kaity N, Kelley, Elizabeth G, Marquardt, Drew
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation energy Antiinfectives and antibacterials Cell death Enthalpy Exchanging Free energy Lipids Neutron scattering Peptides Pore formation Rate constants
Online-Zugang:	Volltext
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