Loop engineering of aryl sulfotransferase B for improving catalytic performance in regioselective sulfation

Catechol sulfates act in our body as important antioxidants and often have anti-inflammatory properties. Enzymatic sulfation of catechol as well as substituted catechols by aryl sulfotransferases opens up an environmentally-friendly route for chemo- and/or regioselective sulfation. This study focuse...

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Veröffentlicht in:	Catalysis science & technology 2020-04, Vol.1 (8), p.2369-2377
Hauptverfasser:	Ji, Yu, Islam, Shohana, Cui, Haiyang, Dhoke, Gaurao V, Davari, Mehdi D, Mertens, Alan M, Schwaneberg, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Aromatic compounds Catalytic activity Catechol Efficiency Molecular docking Reengineering Regioselectivity Stoichiometry Sulfation
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