Quantifying the hygroscopic properties of cyclodextrin containing aerosol for drug delivery to the lungs

Aerosol dynamics is important to quantify in drug delivery to the lungs with the aim of delivering therapeutics to a target location and optimising drug efficacy. The macrocycle (2-hydroxypropyl)-β-cyclodextrin (2-HP-β-CD) is thought to alleviate symptoms associated with neurodegenerative diseases w...

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Veröffentlicht in:	Physical chemistry chemical physics : PCCP 2020-05, Vol.22 (2), p.11327-11336
Hauptverfasser:	Day, C. P. F, Miloserdov, A, Wildish-Jones, K, Pearson, E, Carruthers, A. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Bulk density Chemistry Chemistry, Physical Cyclodextrins Droplets Drug delivery systems Growth factors Hygroscopicity Lungs Morphology Physical Sciences Physics Physics, Atomic, Molecular & Chemical Properties (attributes) Raman spectra Refractivity Relative humidity Respiratory system Science & Technology Signs and symptoms
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