The antagonistic effect of magnesium hydroxide particles on vascular endothelial activation induced by acidic PLGA degradation products

Although drug-eluting stents (DESs) are mainly coated with biodegradable polymers such as PLGA and PLLA, their acidic degradation products can alter the local microenvironment and affect the homeostasis of adjacent tissue. Previously, we developed anti-inflammatory PLGA-based materials including mag...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biomaterials science 2021-02, Vol.9 (3), p.892-97
Hauptverfasser:	Ko, Kyoung-Won, Choi, Bogyu, Kang, Eun Young, Shin, Sang-Woo, Baek, Seung-Woon, Han, Dong Keun
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbable Implants Biodegradability By products Byproducts Cytokines Degradation Drug-Eluting Stents Endothelium, Vascular Homeostasis Magnesium Hydroxide Polylactic acid Polymers Side effects Surgical implants
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!