Straightforward neuron micropatterning and neuronal network construction on cell-repellent polydimethylsiloxane using microfluidics-guided functionalized Pluronic modification

Neuronal cell microengineering involving micropatterning and polydimethylsiloxane (PDMS) microfluidics enables promising advances in microscale neuron control. However, a facile methodology for the precise and effective manipulation of neurons on a cell-repellent PDMS substrate remains challenging....

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Veröffentlicht in:	Analyst (London) 2021-01, Vol.146 (2), p.454-462
Hauptverfasser:	Liu, Wenming, Fu, Wenzhu, Sun, Meilin, Han, Kai, Hu, Rui, Liu, Dan, Wang, Jinyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - drug effects Axons - metabolism Cell Engineering - instrumentation Dendrites - drug effects Dendrites - metabolism Dimethylpolysiloxanes - chemistry Dimethylpolysiloxanes - pharmacology Lab-On-A-Chip Devices Mice Mice, Inbred C57BL Microengineering Microfluidics Micropatterning Nerve Net - cytology Neurons - cytology Neurons - drug effects Neurosciences Optical Imaging Poloxamer - chemistry Polydimethylsiloxane Substrates
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