Continuous-flow synthesis of dimethyl fumarate: a powerful small molecule for the treatment of psoriasis and multiple sclerosis

Dimethyl fumarate (DMF) is a methyl ester of fumaric acid and has recently gained attention due to its use as a pro-drug in different pharmaceutical preparations, besides the low price of the final molecule and no active patents being available for the synthesis of DMF, the prices of multiple sclero...

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Veröffentlicht in:	RSC advances 2020-01, Vol.1 (5), p.249-2494
Hauptverfasser:	Lima, Marcelo T, Finelli, Fernanda G, de Oliveira, Alline V. B, Kartnaller, Vinicius, Cajaiba, João F, Leão, Raquel A. C, de Souza, Rodrigo O. M. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical synthesis Chemistry Continuous flow Fumaric acid Multiple sclerosis Pharmaceuticals Process intensification
Online-Zugang:	Volltext
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