New anionic poly(alkylideneamine) dendrimers as microbicide agents against HIV-1 infection

Acquired immune deficiency syndrome (AIDS) due to human immunodeficiency virus type-1 (HIV-1) represents one of the most important sexually transmitted infections (STI) worldwide. Great international efforts have been made to stop new infections but, to date, several compounds failed as microbicides...

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Veröffentlicht in:	Nanoscale 2019-05, Vol.11 (19), p.9679-969
Hauptverfasser:	Maciel, Dina, Guerrero-Beltrán, Carlos, Ceña-Diez, Rafael, Tomás, Helena, Muñoz-Fernández, M. Ángeles, Rodrigues, João
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anions - chemistry Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Anti-Infective Agents - therapeutic use Carboxylic Acids - chemistry Cell Line Cell Survival - drug effects Dendrimers - chemistry Dendrimers - pharmacology Dendrimers - therapeutic use Female HIV Infections - drug therapy HIV Infections - pathology HIV-1 - drug effects Humans Mice Mice, Inbred BALB C Sulfonic Acids - chemistry Vagina - drug effects Vagina - pathology Virus Internalization - drug effects
Online-Zugang:	Volltext
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