3D QSAR-based design and liquid phase combinatorial synthesis of 1,2-disubstituted benzimidazole-5-carboxylic acid and 3-substituted-5 H -benzimidazo[1,2- d ][1,4]benzodiazepin-6(7 H )-one derivatives as anti-mycobacterial agents

Tuberculosis (TB) is one of the world's deadliest infectious diseases, caused by ( ). In the present study, a 3D QSAR study was performed for the design of novel substituted benzimidazole derivatives as anti-mycobacterial agents. The anti-tubercular activity of the designed compounds was predic...

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Veröffentlicht in:MedChemComm 2019-05, Vol.10 (5), p.817-827
Hauptverfasser: Sitwala, Nikum D, Vyas, Vivek K, Gedia, Piyush, Patel, Kinjal, Bouzeyen, Rania, Kidwai, Saqib, Singh, Ramandeep, Ghate, Manjunath D
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Sprache:eng
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