Trisulfides over disulfides: highly selective synthetic strategies, anti-proliferative activities and sustained H 2 S release profiles

Temperature- and solvent-induced selective synthesis of trisulfides and disulfides is demonstrated. A remarkable selectivity was achieved using Na 2 S as a sulfur-transfer agent under mild, greener, catalyst-free and additive-free conditions. This study reveals trisulfides as a better model than dis...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2019-11, Vol.55 (90), p.13534-13537
Hauptverfasser: Bhattacherjee, Debojit, Sufian, Abu, Mahato, Sulendar K., Begum, Samiyara, Banerjee, Kaustav, De, Sharmistha, Srivastava, Hemant Kumar, Bhabak, Krishna P.
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container_end_page 13537
container_issue 90
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container_title Chemical communications (Cambridge, England)
container_volume 55
creator Bhattacherjee, Debojit
Sufian, Abu
Mahato, Sulendar K.
Begum, Samiyara
Banerjee, Kaustav
De, Sharmistha
Srivastava, Hemant Kumar
Bhabak, Krishna P.
description Temperature- and solvent-induced selective synthesis of trisulfides and disulfides is demonstrated. A remarkable selectivity was achieved using Na 2 S as a sulfur-transfer agent under mild, greener, catalyst-free and additive-free conditions. This study reveals trisulfides as a better model than disulfides in general for a sustained release of H 2 S and potent anti-cancer activities.
doi_str_mv 10.1039/C9CC05562B
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source Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
title Trisulfides over disulfides: highly selective synthetic strategies, anti-proliferative activities and sustained H 2 S release profiles
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