Theragnosis by a miR-141-3p molecular beacon: simultaneous detection and sensitization of 5-fluorouracil resistant colorectal cancer cells through the activation of the TRIM13-associated apoptotic pathway

We developed a molecular beacon targeting miR-141-3p, aberrantly increased in 5-fluorouracil-resistant colorectal cancer cells (R-CRCCs). It consists of a fluorophore-labeled oligonucleotide, antisense to miR-141-3p, and a quencher. It detected R-CRCCs and recovered the chemosensitivity of them to 5...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2019-07, Vol.55 (52), p.7466-7469
Hauptverfasser:	Moon, Sung Ung, Park, Yongkeun, Park, Min Geun, Song, Sung Kyu, Jeong, Seok Hoo, Lee, Yong Seung, Heo, Hye Jung, Jung, Woon Yong, Kim, Soonhag
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Colorectal cancer
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!