Safety assessment in development and operation of modular continuous-flow processes

Improved safety is one of the main drivers for microreactor application in chemical process development and small-scale production. Typical examples of hazardous chemistry are presented indicating potential risks also in miniaturized equipment. Energy balance and kinetic parameters describe the heat...

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Veröffentlicht in:Reaction chemistry & engineering 2017, Vol.2 (3), p.258-28
Hauptverfasser: Kockmann, Norbert, Thenée, Philipp, Fleischer-Trebes, Christoph, Laudadio, Gabriele, Noël, Timothy
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container_end_page 28
container_issue 3
container_start_page 258
container_title Reaction chemistry & engineering
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creator Kockmann, Norbert
Thenée, Philipp
Fleischer-Trebes, Christoph
Laudadio, Gabriele
Noël, Timothy
description Improved safety is one of the main drivers for microreactor application in chemical process development and small-scale production. Typical examples of hazardous chemistry are presented indicating potential risks also in miniaturized equipment. Energy balance and kinetic parameters describe the heat production potential and, together with heat transfer capability, the temperature development in a continuous flow reactor. Besides these calculation procedures, checklists for laboratory safety and risk assessment are the basis for improved laboratory work as well as for equipment-related safety discussions. For complete and larger chemical plants, hazard and operation (HAZOP) studies are the appropriate method of handling hazardous processes and their scale-up. Improved safety is one of the main drivers for microreactor application in chemical process development and small-scale production.
doi_str_mv 10.1039/c7re00021a
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title Safety assessment in development and operation of modular continuous-flow processes
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