An I 2 -mediated cascade reaction of 2'-bromoacetophenones with benzohydrazides/benzamides leading to quinazolino[3,2-b]cinnoline or tryptanthrin derivatives

An efficient and facile protocol for the synthesis of quinazolinone-fused tetracyclic compounds through an iodine-mediated one-pot cascade reaction of 2'-bromoacetophenones with 2-aminobenzohydrazides or 2-aminobenzamides is reported. With 2-aminobenzohydrazides as the substrates, the reaction...

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Veröffentlicht in:	Organic & biomolecular chemistry 2017-02, Vol.15 (6), p.1521-1529
Hauptverfasser:	Guo, Shenghai, Zhai, Jianhui, Fan, Xuesen
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetophenones - chemistry Benzamides - chemistry Heterocyclic Compounds, 2-Ring - chemical synthesis Heterocyclic Compounds, 2-Ring - chemistry Hydrazines - chemistry Iodine - chemistry Molecular Structure Quinazolines - chemical synthesis Quinazolines - chemistry
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