Improvement on binding of chondroitin sulfate derivatives to midkine by increasing hydrophobicity

The interactions between chondroitin sulfate (CS) and a wide number of proteins modulate important biological processes. Here, the binding properties to midkine and pleiotrophin of sulfated, fully protected intermediates, typically obtained in the chemical synthesis of CS oligosaccharides, were test...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic & biomolecular chemistry 2016-04, Vol.14 (14), p.356-359
Hauptverfasser:	de Paz, J. L, Nieto, P. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Chondroitin Sulfates - metabolism Cytokines - metabolism Fluorescence Polarization Hydrophobic and Hydrophilic Interactions
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!